943453-46-1
Chemical Structure
Figitumumab
Synonym(s): CP-751871
- CAS No.: 943453-46-1
- Formula:N/A
- Molecular Weight:(144.5 kDa)
IUPAC Name: 1-(4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)phenyl)-3-oxo-2,7,10,13-tetraoxa-4-azapentadecan-15-yl 2-((2S,4R)-5-(4-hydroxyphenyl)-2-methyl-4-(2-((1R,3R)-4-methyl-3-((2S,3S)-3-methyl-2-((R)-1-methylpiperidine-2-carboxamido)-N-propylpentanamido)-1-propoxypentyl)thiazole-4-carboxamido)pentanoyl)hydrazine-1-carboxylate
SMILES: [Figitumumab]
Biological Activity: Figitumumab (CP-751871) is a potent and fully human monoclonal anti–insulin-like growth factor 1 receptor (IGF1R) antibody. Figitumumab prevents IGF1 from binding to IGF1R with an IC50 of 1.8 nM[1].
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Figitumumab | ≥99.0% | Figitumumab (CP-751871) is a potent and fully human monoclonal anti–insulin-like growth factor 1 receptor (IGF1R) antibody. Figitumumab prevents IGF1 from binding to IGF1R with an IC50 of 1.8 nM. | ||||||||||||||||||||
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Keywords
