946394-50-9
946394-50-9
Chemical Structure
11β-HSD1-IN-14
- CAS No.: 946394-50-9
- Formula:C22H20F3N3O2S
- Molecular Weight:447.47
InChIKey: ONBIFHXEZPQLAZ-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(C2=CC=CC=C2)C=C1)(N3CCN(CC3)C4=NC=CC=C4C(F)(F)F)=O
Biological Activity: 11β-HSD1-IN-14 (Compound 17) is a selective inhibitor for 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1), with IC50 of 74 nM for human HSD1, and 603 nM for HSD1 expressed HEK293 cell[1].
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11β-HSD1-IN-14 | 11β-HSD1-IN-14 (Compound 17) is a selective inhibitor for 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1), with IC50 of 74 nM for human HSD1, and 603 nM for HSD1 expressed HEK293 cell. | |||||||||||||||||||||
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References
Keywords
