958941-60-1
Chemical Structure
CFTR corrector 12
- CAS No.: 958941-60-1
- Formula:C19H21ClN4O2S2
- Molecular Weight:436.98
InChIKey: XERLNCVIGMCAMO-UHFFFAOYSA-N
SMILES: O=C(C(C)(C)C)NC1=NC(C)=C(C2=CSC(NC3=CC(Cl)=CC=C3OC)=N2)S1
Biological Activity: CFTR corrector 12 (compound 17C) is a bithiazole derivative, serving as CFTR corrector. CFTR corrector 12 has the ability to correct some folding defective mutants of the channel responsible for the control of chloride transport across the plasma membrane. CFTR corrector 12 recovers the α-sarcoglycan (α-SG) content in mutant cells[1].
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CFTR corrector 12 | 99.85% | CFTR corrector 12 (compound 17C) is a bithiazole derivative, serving as CFTR corrector. CFTR corrector 12 has the ability to correct some folding defective mutants of the channel responsible for the control of chloride transport across the plasma membrane. CFTR corrector 12 recovers the α-sarcoglycan (α-SG) content in mutant cells. | ||||||||||||||||||||
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Keywords