CFTR corrector 12
Based on 1 Customer Validation
CFTR corrector 12 (compound 17C) is a bithiazole derivative, serving as CFTR corrector. CFTR corrector 12 has the ability to correct some folding defective mutants of the channel responsible for the control of chloride transport across the plasma membrane. CFTR corrector 12 recovers the α-sarcoglycan (α-SG) content in mutant cells.
For research use only. We do not sell to patients.
- Purity: 99.85%
- CAS No.: 958941-60-1
- Formula: C19H21ClN4O2S2
- Molecular Weight:436.98
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 958941-60-1
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Appearance Solid
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Molecular Weight 436.98
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Formula C19H21ClN4O2S2
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Color White to off-white
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SMILES
O=C(C(C)(C)C)NC1=NC(C)=C(C2=CSC(NC3=CC(Cl)=CC=C3OC)=N2)S1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (286.05 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2884 mL | 11.4422 mL | 22.8843 mL | 57.2109 mL |
| 5 mM | 0.4577 mL | 2.2884 mL | 4.5769 mL | 11.4422 mL | |
| 10 mM | 0.2288 mL | 1.1442 mL | 2.2884 mL | 5.7211 mL | |
| 15 mM | 0.1526 mL | 0.7628 mL | 1.5256 mL | 3.8141 mL | |
| 20 mM | 0.1144 mL | 0.5721 mL | 1.1442 mL | 2.8605 mL | |
| 25 mM | 0.0915 mL | 0.4577 mL | 0.9154 mL | 2.2884 mL | |
| 30 mM | 0.0763 mL | 0.3814 mL | 0.7628 mL | 1.9070 mL | |
| 40 mM | 0.0572 mL | 0.2861 mL | 0.5721 mL | 1.4303 mL | |
| 50 mM | 0.0458 mL | 0.2288 mL | 0.4577 mL | 1.1442 mL | |
| 60 mM | 0.0381 mL | 0.1907 mL | 0.3814 mL | 0.9535 mL | |
| 80 mM | 0.0286 mL | 0.1430 mL | 0.2861 mL | 0.7151 mL | |
| 100 mM | 0.0229 mL | 0.1144 mL | 0.2288 mL | 0.5721 mL |
CFTR corrector 12 Related Classifications
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