2. Membrane Transporter/Ion Channel
  3. CFTR
  4. CFTR corrector 12

CFTR corrector 12 (compound 17C) is a bithiazole derivative, serving as CFTR corrector. CFTR corrector 12 has the ability to correct some folding defective mutants of the channel responsible for the control of chloride transport across the plasma membrane. CFTR corrector 12 recovers the α-sarcoglycan (α-SG) content in mutant cells.

For research use only. We do not sell to patients.

CFTR corrector 12 Chemical Structure

CFTR corrector 12 Chemical Structure

CAS No. : 958941-60-1

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CFTR corrector 12 Related Antibodies

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Description

CFTR corrector 12 (compound 17C) is a bithiazole derivative, serving as CFTR corrector. CFTR corrector 12 has the ability to correct some folding defective mutants of the channel responsible for the control of chloride transport across the plasma membrane. CFTR corrector 12 recovers the α-sarcoglycan (α-SG) content in mutant cells[1].

In Vitro

CFTR corrector 12 (compound 17C) (15 μM; 72 h) recovers α-sarcoglycan (α-SG) content in L31P/V247M α-SG mutation cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CFTR corrector 12 Related Antibodies
Molecular Weight

436.98

Formula

C19H21ClN4O2S2
CAS No.
SMILES

O=C(C(C)(C)C)NC1=NC(C)=C(C2=CSC(NC3=CC(Cl)=CC=C3OC)=N2)S1
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CFTR corrector 12 Related Classifications

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Keywords:

CFTR corrector 12958941-60-1CFTR corrector12CFTR corrector-12CFTRCystic fibrosis transmembrane conductance regulatorInhibitorinhibitorinhibit

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