959662-26-1
Chemical Structure
7-Hydroxyneolamellarin A
- CAS No.: 959662-26-1
- Formula:C24H19NO5
- Molecular Weight:401.41
IUPAC Name: 1-(3,4-bis(4-hydroxyphenyl)-1H-pyrrol-1-yl)-2-hydroxy-2-(4-hydroxyphenyl)ethan-1-one
InChIKey: RYIBSKICTMDCHH-UHFFFAOYSA-N
SMILES: OC1=CC=C(C(O)C(N2C=C(C3=CC=C(O)C=C3)C(C4=CC=C(O)C=C4)=C2)=O)C=C1
Biological Activity: 7-Hydroxyneolamellarin A is a natural product that could be derived from sponge Dendrilla nigra. 7-Hydroxyneolamellarin A is a potent hypoxia-inducible factor-1α (HIF-1α) inhibitor. 7-Hydroxyneolamellarin A attenuates the accumulation of hypoxia-inducible factor-1α (HIF-1α) protein and inhibits vascular epidermal growth factor (VEGF) transcriptional activity. 7-Hydroxyneolamellarin A can be used in research of cancer[1].
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7-Hydroxyneolamellarin A | 7-Hydroxyneolamellarin A is a natural product that could be derived from sponge Dendrilla nigra. 7-Hydroxyneolamellarin A is a potent hypoxia-inducible factor-1α (HIF-1α) inhibitor. 7-Hydroxyneolamellarin A attenuates the accumulation of hypoxia-inducible factor-1α (HIF-1α) protein and inhibits vascular epidermal growth factor (VEGF) transcriptional activity. 7-Hydroxyneolamellarin A can be used in research of cancer. | |||||||||||||||||||||
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Keywords
