97-23-4
97-23-4
Chemical Structure
Dichlorophen
Synonym(s): DDM
- CAS No.: 97-23-4
- Formula:C13H10Cl2O2
- Molecular Weight:269.12
IUPAC Name: 2,2'-methylenebis(4-chlorophenol)
InChIKey: MDNWOSOZYLHTCG-UHFFFAOYSA-N
SMILES: OC1=CC=C(Cl)C=C1CC2=CC(Cl)=CC=C2O
Biological Activity: Dichlorophen is a chlorophenol antimicrobial agent that can destroy the integrity of microbial cell membranes and interfere with the activity of metabolic enzymes. Dichlorophen can covalently bind to the thiol groups of microbial proteins and has broad-spectrum antibacterial, antifungal and anthelmintic activity. Dichlorophen can be used as an antimicrobial agent in the study of drug-resistant bacterial infections[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Dichlorophen | 98.55% | Dichlorophen is a chlorophenol antimicrobial agent that can destroy the integrity of microbial cell membranes and interfere with the activity of metabolic enzymes. Dichlorophen can covalently bind to the thiol groups of microbial proteins and has broad-spectrum antibacterial, antifungal and anthelmintic activity. Dichlorophen can be used as an antimicrobial agent in the study of drug-resistant bacterial infections. | ||||||||||||||||||||
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Dichlorophen (Standard) | 98.38% | Dichlorophen (Standard) is the analytical standard of Dichlorophen (HY-12638). This product is intended for research and analytical applications. Dichlorophen is a chlorophenol antimicrobial agent that can destroy the integrity of microbial cell membranes and interfere with the activity of metabolic enzymes. Dichlorophen can covalently bind to the thiol groups of microbial proteins and has broad-spectrum antibacterial, antifungal and anthelmintic activity. Dichlorophen can be used as an antimicrobial agent in the study of drug-resistant bacterial infections. | ||||||||||||||||||||
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PDM2 | 98.96% | PDM2 is a selective, high-affinity aryl hydrocarbon receptor (AhR) antagonist with an Ki of 1.2±0.4 nM. | ||||||||||||||||||||
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Fabl inhibitor 21272541 | 21272541 is a potent inhibitor of FabI protein. 21272541 significantly inhibits the infections caused by Gram-negative organisms. | |||||||||||||||||||||
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Triclosan (Standard) | ≥98% | Triclosan (Standard) is the analytical standard of Triclosan. This product is intended for research and analytical applications. Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC50s of 2 µM and 10 µM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models. | ||||||||||||||||||||
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Clofoctol (Standard) | 98.85% | Clofoctol (Standard) is the analytical standard of Clofoctol. This product is intended for research and analytical applications. Clofoctol is a bacteriostatic antibiotic. Clofoctol is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria. Clofoctol is only functional against Gram-positive bacteria and can penetrate into human lung tissue. Clofoctol is also an inhibitor of prostate cancer. Clofoctol has antiviral potency. | ||||||||||||||||||||
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Iriflophenone (Standard) | ≥98% | Iriflophenone, isolated from Aquilaria sinensis, stimulates MCF-7 and T-47D human breast cancer cells proliferation. | ||||||||||||||||||||
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Benzophenone-2 | 99.66% | Benzophenone-2 (2,2',4,4'-Tetrahydroxybenzophenone) is an organic ultraviolet absorber that is widely used in personal care products and industrial products such as plastics and coatings. Benzophenone-2 is an endocrine disruptor that can interfere with estrogen receptors (ERα receptor) and pregnane X receptor (PXR receptor) activity, leading to reproductive toxicity, immune disorders, and metabolic abnormalities. Benzophenone-2 can inhibit the activity of α-glucosidase (IC50 = 49.72 μM), and can be used for research on diabetes. | ||||||||||||||||||||
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FMP-API-1 | 95.51% | FMP-API-1 is an A-kinase anchoring protein (AKAP)-PKA interaction inhibitor. FMP-API-1 binds to the allosteric site of PKA R subunits and increases the activity of PKA and AQP2 in PKA-knockout cell lines of renal cortical collecting ducts (mpkCCD cells). FMP-API-1 has the potential for the study of nephrogenic diabetes insipidus (NDI). | ||||||||||||||||||||
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3-Chlorobisphenol A | 95.19% | 3-Chlorobisphenol A, a chlorinated derivatives of bisphenol A, is an endocrine-disrupting compound. It binds to estrogen receptors, causing disorders in hormone signaling pathways. Bisphenol A is an industrial chemical used in the production of polycarbonate plastics and epoxy resin. | ||||||||||||||||||||
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Triclosan-13C6 | Triclosan-13C6 is 13C labeled Triclosan. Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC50s of 2 μM and 10 μM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models. | |||||||||||||||||||||
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Triclosan-13C12 | 97.1% | Triclosan-13C12 is 13C labeled Triclosan (HY-B1119). Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC50s of 2 μM and 10 μM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models. | ||||||||||||||||||||
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References
- [1]. Kintz P, et al. Acute fatal poisoning with dichlorophen. Int J Legal Med. 1997;110(2):95-6. [Content Brief]
- [2]. Khaw TH, et al. Identification of Bithionol, Dichlorophen, and Miconazole as Antibacterial Agents against Acinetobacter calcoaceticus. ACS Omega. 2020 Sep 8;5(37):23951-23959. [Content Brief]
