97233-26-6
97233-26-6
Chemical Structure
MDL-19744A
- CAS No.: 97233-26-6
- Formula:C21H25NO3S
- Molecular Weight:371.49
InChIKey: IMKMRGOTDDUQHF-YRFFXBIPSA-N
SMILES: O=C1C2=C(SC(C)=C2)CC[C@H]1CN[C@@H]3[C@@H]([C@H](CC3)OC4=CC=CC=C4)O
Biological Activity: MDL-19744A is an orally active and selective α1-adrenergic receptor antagonist, with rat α1-adrenergic receptor IC50 of 8 nM. MDL-19744A increases renal blood flow, dose-related decreases mean arterial blood pressure, increases urinary sodium excretion, and mediates renal vasodilation. MDL-19744A can be used for the research of hypertension[1].
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MDL-19744A | MDL-19744A is an orally active and selective α1-adrenergic receptor antagonist, with rat α1-adrenergic receptor IC50 of 8 nM. MDL-19744A increases renal blood flow, dose-related decreases mean arterial blood pressure, increases urinary sodium excretion, and mediates renal vasodilation. MDL-19744A can be used for the research of hypertension. | |||||||||||||||||||||
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References
Keywords
