Ac-IETD-AFC TFA

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Ac-IETD-AFC TFA is a synthetic fluorogenic substrate that can be used to specifically detect caspase-8 activity. INDO 1 pentasodium is imbued with the fluorophore AFC (7-amino-4-trifluoromethylcoumarin). When caspase-8 recognizes and cleaves the amide bond following the IETD sequence in this substrate, AFC is released and emits fluorescence (Ex = ~400 nm; Em = ~505 nm).

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  • Formel: C33H39F6N5O14
  • Molecular Weight:843.68
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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Publications Citing Use of MedChemExpress (MCE) Ac-IETD-AFC TFA

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