NOTA trihydrochloride
NOTA (trihydrochloride)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting. NOTA (trihydrochloride) can be used for conjugation of peptides and radionuclides.
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- CAS. Nr.: 133256-65-2
- Formel: C12H24Cl3N3O6
- Molecular Weight:412.69
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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RDC Bifunctional Chelator |
NOTA participates in the synthesis of 68Ga-NOTA-RGD for MicroPET/CT imaging of αvβ3 integrin in rat myocardial infarction[4].
NOTA participates in the synthesis of [68Ga]Ga-NOTA-Nb1053 for immunoPET imaging of multiple myeloma[5].
NOTA is a superior chelator to DOTA for PET imaging with 64Cu-labeled TRC105 in 4T1 murine breast tumor-bearing mice[6].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 133256-65-2
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Molecular Weight 412.69
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Formel C12H24Cl3N3O6
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SMILES
O=C(CN1CCN(CCN(CC1)CC(O)=O)CC(O)=O)O.Cl.Cl.Cl
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)