Cosdosiran sodium
Based on 1 publication(s) in Google Scholar
Cosdosiran sodium is a chemically modified siRNA designed to temporarily inhibit expression of the caspase 2 protein and can be used for the study of nonarteritic anterior ischemic optic neuropathy and other optic neuropathies such as glaucoma that result in the death of retinal ganglion cells.
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- Pureté: 98.48%
- Masse moléculaire:12388.68 (free acid)
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Stockage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications Citing Use of MedChemExpress (MCE) Cosdosiran sodium
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Activité biologique
Chemical Information
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Appearance Solid
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Masse moléculaire 12388.68 (free acid)
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Color White to off-white
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SMILES
[Cosdosiran (sodium)]
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Synonyms
QPI-1007 sodium
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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J Vis Exp
Assessing Microglial Phagocytosis of Myelin Debris in vitro Under Repeated Magnetic Stimulation. [Abstract]2025 Jun 17:(220). PMID: 40622958
Solvant et solubilité
H2O : ≥ 50 mg/mL
* "≥" means soluble, but saturation unknown.
Pureté et documentation
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Fiche technique (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2242 KB)
Références
[1]. Solano EC, Kornbrust DJ, Beaudry A, Foy JW, Schneider DJ, Thompson JD. Toxicological and pharmacokinetic properties of QPI-1007, a chemically modified synthetic siRNA targeting caspase 2 mRNA, following intravitreal injection. Nucleic Acid Ther. 2014;24(4):258-266. doi:10.1089/nat.2014.0489 [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)