Sftpb - surfactant protein B Gene

Also Known as Sp-b

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 192155

Summary

Involved in several processes, including cellular response to mechanical stimulus; cellular response to nitric oxide; and response to vitamin A. Located in alveolar lamellar body; extracellular space; and multivesicular body. Biomarker of asthma; Bacterial pneumonia; lung disease; newborn respiratory distress syndrome; and obesity. Human ortholog(s) of this gene implicated in lung disease (multiple); respiratory syncytial virus infectious disease; and toxic shock syndrome. Orthologous to human SFTPB (surfactant protein B). [provided by Alliance of Genome Resources, Apr 2022]

Sftpb Products (1)

mRNA Protein Name
NM_138842.2 NP_620197.2 pulmonary surfactant-associated protein B precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in cellular response to mechanical stimulus IEP
IEP: Inferred from expression pattern
12600831 RGD
involved in cellular response to nitric oxide IEP
IEP: Inferred from expression pattern
15640287 RGD
involved in circadian rhythm IEP
IEP: Inferred from expression pattern
12872443 RGD
involved in response to Thyroglobulin triiodothyronine IEP
IEP: Inferred from expression pattern
1850607 RGD
involved in response to cAMP IEP
IEP: Inferred from expression pattern
1850607 RGD
involved in response to dexamethasone IEP
IEP: Inferred from expression pattern
1850607 RGD
involved in response to epidermal growth factor IEP
IEP: Inferred from expression pattern
19781387 RGD
involved in response to glucocorticoid IEP
IEP: Inferred from expression pattern
10830305 RGD
involved in response to glucose IEP
IEP: Inferred from expression pattern
10027080 RGD
involved in response to growth factor IEP
IEP: Inferred from expression pattern
17267143 RGD
involved in response to hyperoxia IEP
IEP: Inferred from expression pattern
11472975 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
14756961 RGD
involved in response to interleukin-6 IEP
IEP: Inferred from expression pattern
11000512 RGD
involved in response to leptin IEP
IEP: Inferred from expression pattern
11839533 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
11000512 RGD
involved in response to vitamin A IEP
IEP: Inferred from expression pattern
10385596 RGD
Cellular Component GO Annotation Evidence References Source
located in alveolar lamellar body IDA
IDA: Inferred from direct assay
2475034 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
11704537 RGD
located in multivesicular body IDA
IDA: Inferred from direct assay
16187065 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pulmonary surfactant-associated protein B

  • pulmonary surfactant-associated proteolipid SPL(Phe)

  • surfactant associated protein B

  • surfactant, pulmonary-associated protein B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12782 SFTPB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22802 Sftpb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sftpb NCBI NCBI:6439