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Cat. No.: HY-170305

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E3 Ligase Ligand-linker Conjugate 145

E3 Ligase Ligand-linker Conjugate 145 is a conjugate of E3 ubiquitin ligase ligand + Linker, used for the synthesis of PROTAC AR Degrader-7 (HY-160221).

For research use only. We do not sell to patients.

Formula: C₂₃H₂₆FN₅O₄
Molecular Weight:455.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

E3 Ligase Ligand-linker Conjugate 145 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

E3 Ligase Ligand-linker Conjugate 145 is a conjugate of E3 ubiquitin ligase ligand + Linker, used for the synthesis of PROTAC AR Degrader-7 (HY-160221)^[1].

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

Molecular Weight 455.48
Formula C₂₃H₂₆FN₅O₄
SMILES

O=C1N(C(C2=C1C=C(N3C[C@]([H])([C@H]4CN5CCNCC5)[C@]4(C3)[H])C(F)=C2)=O)C6CCC(NC6=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. DU wu,et al. Dual-function chimeric heterocyclic compound for targeted degradation of androgen receptor and application thereof. CN111825657A. 2020.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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E3 Ligase Ligand-linker Conjugate 145

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Biological Activity
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Chemical Information
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References

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E3 Ligase Ligand-linker Conjugate 145

All E3 Ligase Ligand-Linker Conjugates Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

E3 Ligase Ligand-linker Conjugate 145 Related Classifications

HY-170305 Related Classifications

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