2. Immunology/Inflammation
  3. NO Synthase
  4. Floridolide B

Floridolide B is a clerodane-type diterpenoid that can be isolated from the tuberous roots of Tinospora sagittata(Oliv.) Gagnep. The IC50 value of Floridolide B for inhibiting NO production in LPS-stimulated microglia is >60 μM.

For research use only. We do not sell to patients.

Floridolide B

Floridolide B Chemical Structure

CAS No. : 67517-03-7

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Floridolide B Related Antibodies

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Description

Floridolide B is a clerodane-type diterpenoid that can be isolated from the tuberous roots of Tinospora sagittata(Oliv.) Gagnep. The IC50 value of Floridolide B for inhibiting NO production in LPS-stimulated microglia is >60 μM[1].

In Vitro

Floridolide B (1.875-60 μM; 1 h pre-incubation, then 24 h co-incubation with LPS) shows poor inhibition of NO production in LPS-stimulated BV-2 cells, with an IC50 value greater than 60 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Floridolide B Related Antibodies
Molecular Weight

348.43

Formula

C20H28O5
CAS No.
SMILES

C[C@]12[C@](CCC=C2C(O)=O)([H])[C@@](C)([C@H](CC1)CO)CCC3=CCOC3=O
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Floridolide B Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Floridolide B67517-03-7NO SynthaseNitric oxide synthasesNOSTinospora sagittata (Oliv.) GagnepNO productionclerodane diterpenoidLPS-stimulated microglial cellsBV-2 cellsInhibitorinhibitorinhibit

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