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Referencia número: HY-N19700

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Calphostin D

Calphostin D is a protein kinase C (Protein Kinase, PKC) inhibitor with an IC₅₀ of 6.4 μM. Calphostin D achieves selective inhibition by interacting with the unique C1 regulatory domain of PKC. As a photosensitizer, Calphostin D generates reactive oxygen species upon exposure to light. Calphostin D can be used in cancer-related research.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 124986-26-1
Fòrmula: C₃₀H₃₀O₁₀
Peso molecular:550.55

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Calphostin D Chemical Structure

No. CAS: 124986-26-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Descripciòn

IC₅₀ & Target^[1]

PKC

6.4 μM (IC₅₀)

Ver todos los productos específicos de isoformas PKC :

In Vitro

Calphostin D inhibits full-length PKC with an IC₅₀ of 6.4 μM, acting via the enzyme's regulatory domain^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 124986-26-1
Peso molecular 550.55
Fòrmula C₃₀H₃₀O₁₀
SMILES

O=C(C1=C2C(C3=C(OC)C=C(O)C4=C53)=C(OC)C=C1O)C(OC)=C(C[C@H](O)C)C2=C5C(C[C@H](O)C)=C(OC)C4=O
Structure Classification
- Phenols
- Polyphenols
Initial Source
- Microorganisms
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Morgan BJ, et al. Design, synthesis, and investigation of protein kinase C inhibitors: total syntheses of (+)-calphostin D, (+)-phleichrome, cercosporin, and new photoactive perylenequinones. Journal of the American Chemical Society. 2009 Jul 08;131(26):9413-25. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Calphostin D

Ver todos los productos específicos de isoformas PKC

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

Calphostin D Related Classifications

HY-N19700 Related Classifications