PRMT5-IN-45
PRMT5-IN-45 (compound 36) is a potent and selective PRMT5 inhibitor with an IC50 of 3 nM. PRMT5-IN-45 potently reduces the level of symmetric dimethylarginines (sDMA) and inhibits the proliferation of MOLM-13 cell lines by inducing apoptosis and cell cycle arrest.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C26H31N7O2
- Peso molecular:473.57
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Ver todos los productos específicos de isoformas Histone Methyltransferase
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Actividad biológica
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PRMT5 3 nM (IC50) |
Chemical Information
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Peso molecular 473.57
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Fòrmula C26H31N7O2
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SMILES
O[C@@H]1[C@H](O)[C@@H](CCC2=CC=C3C=CC(N)=NC3=C2)C[C@H]1N4C=CC5=C(N6CCNCC6)N=CN=C54
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)