SAR107375
SAR107375 is a potent and orally active dual thrombin and factor Xa inhibitor, with Ki values of 1 nM and 8 nM for factor Xa and thrombin, respectively.
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- No. CAS: 1184300-63-7
- Fòrmula: C24H30ClN5O5S2
- Peso molecular:568.11
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
Ki: 1 nM (thrombin), 8 nM (factor Xa)[1].
Chemical Information
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No. CAS 1184300-63-7
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Peso molecular 568.11
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Fòrmula C24H30ClN5O5S2
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SMILES
O=C(C1=CC=C(Cl)S1)NC[C@H](NS(=O)(C2=CC=CC(N3C(CCC3)=O)=C2C)=O)C(N4CCN(C)CC4)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Jerome Meneyrol, et al. 5-Chlorothiophene-2-carboxylic acid [(S)-2-[2-methyl-3-(2-oxopyrrolidin-1-yl)benzenesulfonylamino]-3-(4-methylpiperazin-1-yl)-3-oxopropyl]amide (SAR107375), a selective and potent orally active dual thrombin and factor Xa inhibitor. J Med Chem. 2013 Dec 12;56(23):9441-56. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SAR107375 Related Classifications
HY-12605 Related Classifications
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