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FLT4 - fms related receptor tyrosine kinase 4 Gene

Species: Sus scrofa

Gene Type: protein coding

Gene ID: 100518179

About FLT4

Primary_assembly 2: 78,076,080-78,115,126 forward strand.Sscrofa11.1:CM000813.5

This gene has 4 transcripts (splice variants), 196 orthologues and 52 paralogues. Ubiquitous expression in liver (RPKM 7.), lung (RPKM 5.4) and 8 other tissues.

FLT4 Products (1)

mRNA	Protein	Name
XM_021084312.1	XP_020939971.1	vascular endothelial growth factor receptor 3

FLT4 Protein Structure

Ig_2

IgI_VEGFR

IgI_VEGFR-3

IG_like

VEGFR-2_TMD

PKc_like

0
300
600
900
1200
1369 a.a.

Protein Preferred Names	Protein Names
vascular endothelial growth factor receptor 3	fms related tyrosine kinase 4

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-10260	Vandetanib	99.85%	Yes
HY-10260B	Vandetanib hydrochloride	/	Unkown
HY-10260A	Vandetanib trifluoroacetate	/	Unkown

Clinical Phase

Bioactive Molecules (7)

Cat. No.	Product Name	Effect	Purity	Phase
HY-10205	Cediranib		99.87%	Phase 3
HY-100019	Rogaratinib	Inhibitor	99.86%	Phase 3
HY-13049	Cediranib maleate		99.95%	Phase 3
HY-110272	Vatalanib succinate	Inhibitor	/	Phase 3
HY-13034	Gandotinib	Inhibitor	99.86%	Phase 2
HY-10987A	ENMD-2076		99.99%	Phase 2
HY-10987	ENMD-2076 Tartrate		99.66%	Phase 2

Pre-clinical Phase

Bioactive Molecules (16)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-116624	MAZ51		99.96%	Unkown
HY-15813	FIIN-1	Inhibitor	99.04%	Unkown
HY-119933	RIPK1-IN-7	Inhibitor	98.56%	Unkown
HY-145293	TNIK-IN-3	Inhibitor	99.79%	Unkown
HY-RS04994	FLT4 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-10260S	Vandetanib-d6		/	Unkown
HY-10260S1	Vandetanib-d4		/	Unkown
HY-10260S2	Vandetanib-13C6		/	Unkown
HY-155178	Antiproliferative agent-34	Inhibitor	/	Unkown
HY-168114	Multi-kinase inhibitor 3	Inhibitor	/	Unkown
HY-168115	Multi-kinase inhibitor 4	Inhibitor	/	Unkown
HY-173124	CDK2/FLT4/PDGFRA-IN-1		/	Unkown
HY-182354	VEGFR2-IN-84	Inhibitor	/	Unkown
HY-RS04995	Flt4 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS04996	Flt4 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-174683	Human FLT4 mRNA		/	Unkown

Bioactive MoleculesInhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P990620	LY3022856	Inhibitor	98.84%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	FLT4	NCBI	NCBI:2324