Multi-kinase inhibitor 4
Multi-kinase inhibitor 4 (compound 14) is an orally active inhibitor of FLT1, KDR, FLT3, FLT4, PDGFRα, PDGFRβ, with IC50s of 1.97 nM, 1.04 nM, 0.33 nM, 1.44 nM, 0.18 nM, 0.89 nM. Multi-kinase inhibitor 4 plays an important role in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 2648279-77-8
- Formula: C25H24N6O2
- Molecular Weight:440.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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PDGFRα 0.18 nM (IC50) |
PDGFRβ 0.89 nM (IC50) |
Chemical Information
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CAS No. 2648279-77-8
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Molecular Weight 440.50
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Formula C25H24N6O2
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SMILES
O=C(NC1=CC(C(C)(C)C)=NO1)CC(C=C2)=CC=C2N3C4=CC=C(C5=CNN=C5)C=C4N=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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