2648279-77-8
2648279-77-8
Chemical Structure
Multi-kinase inhibitor 4
- CAS No.: 2648279-77-8
- Formula:C25H24N6O2
- Molecular Weight:440.50
InChIKey: KLCBEXKZLLKSAW-UHFFFAOYSA-N
SMILES: O=C(NC1=CC(C(C)(C)C)=NO1)CC(C=C2)=CC=C2N3C4=CC=C(C5=CNN=C5)C=C4N=C3
Biological Activity: Multi-kinase inhibitor 4 (compound 14) is an orally active inhibitor of FLT1, KDR, FLT3, FLT4, PDGFRα, PDGFRβ, with IC50s of 1.97 nM, 1.04 nM, 0.33 nM, 1.44 nM, 0.18 nM, 0.89 nM. Multi-kinase inhibitor 4 plays an important role in cancer research[1].
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Multi-kinase inhibitor 4 | Multi-kinase inhibitor 4 (compound 14) is an orally active inhibitor of FLT1, KDR, FLT3, FLT4, PDGFRα, PDGFRβ, with IC50s of 1.97 nM, 1.04 nM, 0.33 nM, 1.44 nM, 0.18 nM, 0.89 nM. Multi-kinase inhibitor 4 plays an important role in cancer research. | |||||||||||||||||||||
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References
Keywords
