PIKFYVE - phosphoinositide kinase, FYVE-type zinc finger containing Gene
Species: Sus scrofa
Gene Type: protein coding
Gene ID: 100521692
About PIKFYVE
Primary_assembly 15: 111,372,173-111,467,899 forward strand.Sscrofa11.1:CM000826.5
This gene has 6 transcripts (splice variants), 205 orthologues and 14 paralogues. Ubiquitous expression in kidney (RPKM 5.9), lung (RPKM 3.9) and 8 other tissues.
PIKFYVE Products (15)
| mRNA | Protein | Name |
|---|---|---|
| XM_013984435.2 | XP_013839889.1 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 |
| XM_013984438.2 | XP_013839892.1 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X4 |
| XM_021076160.1 | XP_020931819.1 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X7 |
| XM_021076168.1 | XP_020931827.1 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X11 |
| XM_013984439.2 | XP_013839893.1 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X5 |
| XM_021076162.1 | XP_020931821.1 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X8 |
| XM_013984436.2 | XP_013839890.1 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X2 |
| XM_021076161.1 | XP_020931820.1 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X7 |
| XM_021076167.1 | XP_020931826.1 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X10 |
| XM_013984437.2 | XP_013839891.1 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X3 |
| XM_013984440.2 | XP_013839894.1 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X6 |
| XM_021076165.1 | XP_020931824.1 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X9 |
| XM_021076166.1 | XP_020931825.1 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X10 |
| XM_021076163.1 | XP_020931822.1 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X8 |
| XM_013984434.2 | XP_013839888.1 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 |
PIKFYVE Protein Structure
FYVE_PIKfyve_Fab1
FYVE_PIKfyve_Fab1: cd15725 (165 - 226)
DEP_PIKfyve
DEP_PIKfyve: cd04448 (368 - 449)
Fab1_TCP
Fab1_TCP: cd03334 (628 - 888)
PIPKc_PIKfyve
PIPKc_PIKfyve: cd17300 (1829 - 2095)
- 0
- 400
- 800
- 1200
- 1600
- 2000
- 2110 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
1-phosphatidylinositol 3-phosphate 5-kinase |
|
Related Agents
- Clinical Phase
- Pre-clinical Phase
Clinical Phase
Bioactive Molecules
(2)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-14644 | Apilimod | Inhibitor | 99.80% | Phase 2 |
| HY-14644A | Apilimod mesylate | Inhibitor | 99.58% | Phase 2 |
Pre-clinical Phase
Bioactive Molecules
(18)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-118630 | Vacuolin-1 | Inhibitor | 98.54% | Unkown |
| HY-13228 | YM-201636 | Inhibitor | 98.07% | Unkown |
| HY-15982 | APY0201 | Inhibitor | 99.42% | Unkown |
| HY-119624 | MOMIPP | Inhibitor | 99.00% | Unkown |
| HY-155994 | PIK5-12d | Degrader | 99.15% | Unkown |
| HY-151473 | PIKfyve-IN-1 | Inhibitor | 99.64% | Unkown |
| HY-160477 | DC-SX029 | Inhibitor | 98.07% | Unkown |
| HY-153119 | TMX-4153 | Degrader | 98.96% | Unkown |
| HY-161619 | RMC-113 | Inhibitor | 99.54% | Unkown |
| HY-159625 | WX8 | Inhibitor | 99.43% | Unkown |
| HY-154956 | PIKfyve-IN-2 | Inhibitor | 98.0% | Unkown |
| HY-163943 | UNI418 | Inhibitor | 99.61% | Unkown |
| HY-163133 | PIKfyve-IN-3 | 99.55% | Unkown | |
| HY-170909 | PIKfyve-IN-4 | Inhibitor | 99.53% | Unkown |
| HY-123876 | AS2677131 | Inhibitor | / | Unkown |
| HY-177432 | TMX-4140 | Inhibitor | / | Unkown |
| HY-177091 | AS2795440 | Inhibitor | / | Unkown |
| HY-175631 | PIKfyve ligand-1 | Degrader | / | Unkown |
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