Adamts9 - a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9 Gene

Also Known as UND3; UND4; Gsfund3; Mhdaund3; Mhdaund4; 1810011L16Rik; 8430403M15Rik; E030027K14Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 101401

Summary

Enables endopeptidase activity. Involved in several processes, including circulatory system development; negative regulation of endothelial cell migration; and negative regulation of sprouting angiogenesis. Acts upstream of or within positive regulation of melanocyte differentiation; proteolysis; and response to bacterium. Located in cell surface and extracellular space. Is expressed in several structures, including alimentary system; cardiovascular system; embryo mesenchyme; eye; and genitourinary system. Orthologous to human ADAMTS9 (ADAM metallopeptidase with thrombospondin type 1 motif 9). [provided by Alliance of Genome Resources, Apr 2022]

Adamts9 Products (1)

mRNA Protein Name
NM_175314.4 NP_780523.3 A disintegrin and metalloproteinase with thrombospondin motifs 9 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables endopeptidase activity IDA
IDA: Inferred from direct assay
18454205 MGI
Biological Process GO Annotation Evidence References Source
involved in aorta morphogenesis IMP
IMP: Inferred from mutant phenotype
20096780 MGI
acts upstream of or within camera-type eye morphogenesis IMP
IMP: Inferred from mutant phenotype
27687499 MGI
acts upstream of or within cornea development in camera-type eye IMP
IMP: Inferred from mutant phenotype
27687499 MGI
involved in endothelial cell-matrix adhesion IMP
IMP: Inferred from mutant phenotype
20093484 MGI
involved in extracellular matrix organization IMP
IMP: Inferred from mutant phenotype
20096780 MGI
involved in heart valve morphogenesis IMP
IMP: Inferred from mutant phenotype
20096780 MGI
acts upstream of or within lens development in camera-type eye IMP
IMP: Inferred from mutant phenotype
27687499 MGI
acts upstream of melanocyte differentiation IGI
IGI: Inferred from genetic interaction
18454205 MGI
involved in negative regulation of endothelial cell migration IMP
IMP: Inferred from mutant phenotype
20093484 MGI
involved in negative regulation of sprouting angiogenesis IMP
IMP: Inferred from mutant phenotype
20093484 MGI
acts upstream of or within positive regulation of melanocyte differentiation IGI
IGI: Inferred from genetic interaction
18454205 MGI
acts upstream of or within proteolysis IDA
IDA: Inferred from direct assay
18454205 MGI
acts upstream of or within regulation of developmental pigmentation IGI
IGI: Inferred from genetic interaction
18454205 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
involved in ventricular cardiac muscle tissue development IMP
IMP: Inferred from mutant phenotype
20096780 MGI
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
24220035 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
18454205 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

A disintegrin and metalloproteinase with thrombospondin motifs 9

  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00309 ADAMTS9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19831 Adamts9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26328 Adamts9 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adamts9 NCBI NCBI:56999