PLK3 - polo like kinase 3 Gene

Species: Macaca fascicularis

Gene Type: protein coding
Gene ID: 102130926

About PLK3

Primary_assembly 1: 179,272,627-179,277,784 reverse strand.Macaca_fascicularis_6.0:CM021939.1

This gene has 1 transcript (splice variant), 203 orthologues and 4 paralogues.

PLK3 Products (2)

mRNA Protein Name
XM_045372271.1 XP_045228206.1 serine/threonine-protein kinase PLK3 isoform X1
XM_005543561.3 XP_005543618.1 serine/threonine-protein kinase PLK3 isoform X2

PLK3 Protein Structure

STKc_PLK3

STKc_PLK3: cd14189 (59 - 313)

POLO_box_1

POLO_box_1: cd13118 (460 - 548)

POLO_box_2

POLO_box_2: cd13117 (561 - 628)

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  • 500
  • 600
  • 647 a.a.
Protein Preferred Names Protein Names

serine/threonine-protein kinase PLK3

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12137 Volasertib Inhibitor 99.97% Yes
HY-12137A Volasertib trihydrochloride Inhibitor 99.12% Yes

Clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Phase
HY-50698 BI 2536 Inhibitor 99.95% Phase 2
HY-147298 Plogosertib Inhibitor 98.59% Phase 2
HY-15160 TAK-960 Inhibitor 99.75% Phase 1
HY-15160B TAK-960 dihydrochloride Inhibitor 99.15% Phase 1
HY-15160A TAK-960 hydrochloride Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (16)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-10197 Wortmannin Inhibitor 99.86% Unkown
HY-100789 ON1231320 Inhibitor 99.90% Unkown
HY-11003 GW843682X Inhibitor 99.89% Unkown
HY-12134 Poloxin Inhibitor 98.05% Unkown
HY-108597 TC-S 7005 Inhibitor 99.68% Unkown
HY-15158 SBE13 Hydrochloride Inhibitor 98.56% Unkown
HY-18009 (Z)-LFM-A13 Inhibitor 99.80% Unkown
HY-110002 LFM-A13 Inhibitor 99.65% Unkown
HY-173212 PLK1-IN-13 Inhibitor / Unkown
HY-149100 PLK1-IN-6 Inhibitor / Unkown
HY-15158A SBE13 Inhibitor / Unkown
HY-172364 PLK1-IN-12 Inhibitor / Unkown
HY-115589 YLT-11 Inhibitor / Unkown
HY-111090 GSK461364 analogue 1 Inhibitor / Unkown
HY-181051 PLK1-IN-16 Inhibitor / Unkown
HY-181030 BDE30671203 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PLK3 NCBI NCBI:1263