MDM2 - MDM2 proto-oncogene Gene

Species: Macaca fascicularis

Gene Type: protein coding
Gene ID: 102136323

About MDM2

Primary_assembly 11: 68,110,692-68,145,626 forward strand.Macaca_fascicularis_6.0:CM021949.1

This gene has 9 transcripts (splice variants), 253 orthologues and 1 paralogue.

MDM2 Products (9)

mRNA Protein Name
XM_045365591.1 XP_045221526.1 E3 ubiquitin-protein ligase Mdm2 isoform X3
XM_045365590.1 XP_045221525.1 E3 ubiquitin-protein ligase Mdm2 isoform X2
XM_045365592.1 XP_045221527.1 E3 ubiquitin-protein ligase Mdm2 isoform X4
XM_005571500.3 XP_005571557.1 E3 ubiquitin-protein ligase Mdm2 isoform X2
XM_015431184.2 XP_015286670.1 E3 ubiquitin-protein ligase Mdm2 isoform X2
XM_045365594.1 XP_045221529.1 E3 ubiquitin-protein ligase Mdm2 isoform X6
XM_045365593.1 XP_045221528.1 E3 ubiquitin-protein ligase Mdm2 isoform X5
XM_045365589.1 XP_045221524.1 E3 ubiquitin-protein ligase Mdm2 isoform X2
XM_005571498.3 XP_005571555.1 E3 ubiquitin-protein ligase Mdm2 isoform X1

MDM2 Protein Structure

MDM2

MDM2: cd17672 (30 - 112)

zf-RanBP

zf-RanBP: pfam00641 (304 - 333)

mRING-HC-C2H2C4_MDM2

mRING-HC-C2H2C4_MDM2: cd16783 (440 - 496)

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  • 100
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  • 400
  • 497 a.a.
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase Mdm2

  • MDM2 oncogene, E3 ubiquitin protein ligase

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-N0004 Oridonin 99.89% Phase 4

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-130684 MDM2 ligand 5 98.02% Unkown
HY-128837 Nutlin carboxylic acid 98.63% Unkown
HY-P5930 HOXB7 8–25 / Unkown
HY-128837A (rel)-Nutlin carboxylic acid / Unkown
HY-128836 (4R,5S)-Nutlin carboxylic acid / Unkown
HY-168280 AS1411-C4-VH032 Degrader / Unkown
HY-148106 MEL23 Inhibitor / Unkown
HY-181813 PROTAC DHFR Degrader-1 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MDM2 NCBI NCBI:4193