1. Apoptosis
  2. MDM-2/p53
  3. MDM2-IN-1

MDM2-IN-1 

Cat. No.: HY-130684 Purity: 95.13% ee.: 100%
Handling Instructions

MDM2-IN-1 (Compound 30) is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans (D-)configuration.

For research use only. We do not sell to patients.

MDM2-IN-1 Chemical Structure

MDM2-IN-1 Chemical Structure

CAS No. : 1410737-09-5

Size Price Stock Quantity
5 mg USD 500 In-stock
Estimated Time of Arrival: December 31
10 mg USD 850 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1800 In-stock
Estimated Time of Arrival: December 31
50 mg USD 3100 In-stock
Estimated Time of Arrival: December 31
100 mg USD 4700 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

MDM2-IN-1 (Compound 30) is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans (D-)configuration[1].

Molecular Weight

463.33

Formula

C₂₃H₂₁Cl₂FN₂O₃

CAS No.

1410737-09-5

SMILES

O=C([[email protected]](N1)[[email protected]](C2=CC=CC(Cl)=C2F)[[email protected]]3(C(NC4=C3C=CC(Cl)=C4)=O)C51CCCCC5)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 22.5 mg/mL (48.56 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1583 mL 10.7914 mL 21.5829 mL
5 mM 0.4317 mL 2.1583 mL 4.3166 mL
10 mM 0.2158 mL 1.0791 mL 2.1583 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.25 mg/mL (4.86 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

MDM2-IN-1MDM-2/p53Trans-configurationInhibitorinhibitorinhibit

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Product Name:
MDM2-IN-1
Cat. No.:
HY-130684
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