Ano10 - anoctamin 10 Gene

Also Known as Tmem16k

Species: Mus musculus

Gene Type: protein coding
Gene ID: 102566

Summary

This gene encodes a member of the anoctamin family, which in mammals is comprised of 10 members. Anoctamin proteins are proposed to have eight transmembrane domains with both termini facing the cytoplasm and a C-terminal domain of unknown function. While some members have been characterized as calcium-activated chloride channels, this protein is reported to inhibit anion conductance. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Dec 2012]

Ano10 Products (2)

mRNA Protein Name
NM_001271873.1 NP_001258802.1 anoctamin-10 isoform 2
NM_133979.3 NP_598740.1 anoctamin-10 isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
NOT enables intracellularly calcium-gated chloride channel activity IDA
IDA: Inferred from direct assay
23532839 MGI
NOT enables phospholipid scramblase activity IDA
IDA: Inferred from direct assay
23532839 MGI
Cellular Component GO Annotation Evidence References Source
located in intracellular anatomical structure IDA
IDA: Inferred from direct assay
20056604 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
20056604 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

anoctamin-10

  • transmembrane protein 16K

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16254 Ano10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00741 ANO10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ano10 NCBI NCBI:55129