2. Gene
  3. SMPDL3A - sphingomyelin phosphodiesterase acid like 3A Gene

SMPDL3A - sphingomyelin phosphodiesterase acid like 3A Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ASM3A; ASML3a; yR36GH4.1

Gene ID: 10924 | Gene type: protein coding

About SMPDL3A

Cytogenetic location: 6q22.31 Genomic coordinates (GRCh38): 6:122,789,258-122,809,720 (from NCBI)

This gene has 3 transcripts (splice variants), 197 orthologues and 2 paralogues. Ubiquitous expression in colon (RPKM 18.5), small intestine (RPKM 18.4) and 25 other tissues.

Summary

Enables phosphoric diester hydrolase activity and zinc ion binding activity. Involved in nucleoside triphosphate catabolic process. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

SMPDL3A Products(2)

mRNA Protein Name
NM_001286138.2 NP_001273067.1 acid sphingomyelinase-like phosphodiesterase 3a isoform b
NM_006714.5 NP_006705.1 acid sphingomyelinase-like phosphodiesterase 3a isoform a precursor

SMPDL3A Protein Structure

Metallophos

Metallophos: Calcineurin-like phosphoesterase (40 - 296)

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  • 453 a.a.
Protein Preferred Names Protein Names

acid sphingomyelinase-like phosphodiesterase 3a

0610010C24Rik

Recombinant SMPDL3A Proteins

Cat. No. Product Name Accession Purity
HY-P71325 SMPDL3A Protein, Human (HEK293, His) Q92484 (L23-Y453) ≥95%

Related Diseases

Diseases Alias
Polycystic Echinococcosis

Human Polycystic Hydatid Disease

Neotropical Echinococcosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13451 SMPDL3A Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus SMPDL3A RGD RGD:1359277
Bos taurus SMPDL3A VGNC VGNC:35033
Felis catus SMPDL3A VGNC VGNC:65504
Mus musculus SMPDL3A MGD MGI:1931437
Macaca mulatta SMPDL3A VGNC VGNC:77731
Canis familiaris SMPDL3A VGNC VGNC:46573
Others SMPDL3A NCBI