Prps2 - phosphoribosyl pyrophosphate synthetase 2 Gene

Also Known as Prps-2; 2610101M19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 110639

Summary

Predicted to enable several functions, including magnesium ion binding activity; purine ribonucleotide binding activity; and ribose phosphate diphosphokinase activity. Predicted to be involved in 5-phosphoribose 1-diphosphate biosynthetic process and AMP biosynthetic process. Predicted to act upstream of or within phosphorylation. Predicted to be part of ribose phosphate diphosphokinase complex. Predicted to be active in cytoplasm. Is expressed in alimentary system; central nervous system; and retina. Orthologous to human PRPS2 (phosphoribosyl pyrophosphate synthetase 2). [provided by Alliance of Genome Resources, Apr 2022]

Prps2 Products (2)

mRNA Protein Name
NM_001313758.1 NP_001300687.1 ribose-phosphate pyrophosphokinase 2 isoform 1
NM_026662.5 NP_080938.1 ribose-phosphate pyrophosphokinase 2 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ribose phosphate diphosphokinase activity IDA
IDA: Inferred from direct assay
26175007 MGI
enables ribose phosphate diphosphokinase activity IMP
IMP: Inferred from mutant phenotype
24855946 MGI
Biological Process GO Annotation Evidence References Source
involved in 5-phosphoribose 1-diphosphate biosynthetic process IDA
IDA: Inferred from direct assay
26175007 MGI
involved in 5-phosphoribose 1-diphosphate biosynthetic process IMP
IMP: Inferred from mutant phenotype
24855946 MGI
involved in pentose-phosphate shunt IMP
IMP: Inferred from mutant phenotype
24855946 MGI
Cellular Component GO Annotation Evidence References Source
is active in cytosol IDA
IDA: Inferred from direct assay
26175007 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ribose-phosphate pyrophosphokinase 2

  • PRS-II

  • phosphoribosyl pyrophosphate synthase II

  • phosphoribosyl pyrophosphate synthetase II

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11220 PRPS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18836 Prps2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25328 Prps2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prps2 NCBI NCBI:5634