Pip4k2c - phosphatidylinositol-5-phosphate 4-kinase type 2 gamma Gene

Also Known as Pip5k2c

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 140607

Summary

Enables 1-phosphatidylinositol-4-phosphate 5-kinase activity. Predicted to be involved in several processes, including 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process; negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity; and positive regulation of autophagosome assembly. Located in endoplasmic reticulum. Orthologous to human PIP4K2C (phosphatidylinositol-5-phosphate 4-kinase type 2 gamma). [provided by Alliance of Genome Resources, Apr 2022]

Pip4k2c Products (1)

mRNA Protein Name
NM_080480.2 NP_536728.2 phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Verweise Source
enables 1-phosphatidylinositol-4-phosphate 5-kinase activity IDA
IDA: Inferred from direct assay
9685379 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

  • PI(5)P 4-kinase type II gamma

  • PIP4KII-gamma

  • phosphatidylinositol 5-phosphate 4-kinase type II gamma

  • phosphatidylinositol-4-phosphate 5-kinase, type II, gamma

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (2)
Art. -Nr. Produktname Wirkung
Reinheit Phase
HY-106005 MMV390048 Inhibitor 98.85% Phase 2
HY-175751 LRK-4189 Modulator / Phase 2

Pre-clinical Phase

Bioactive Molecules (14)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-110150 UNC3230 Inhibitor 99.39% Unkown
HY-134508 C24-Ceramide Activator 99.92% Unkown
HY-164827 CDK2 degrader 3 Degrader 99.91% Unkown
HY-112440 HZX-02-059 Inhibitor 99.40% Unkown
HY-15800A CZC-25146 Inhibitor 98.05% Unkown
HY-153119 TMX-4153 Degrader 98.96% Unkown
HY-159625 WX8 Inhibitor 99.43% Unkown
HY-161619 RMC-113 99.54% Unkown
HY-174296 TMX-4102 / Unkown
HY-177432 TMX-4140 Inhibitor / Unkown
HY-RS10564 PIP4K2C Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-15800 CZC-25146 hydrochloride Inhibitor / Unkown
HY-RS18440 Pip4k2c Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24922 Pip4k2c Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pip4k2c NCBI NCBI:79837