DPY19L3 - dpy-19 like C-mannosyltransferase 3 Gene

Homo sapiens

Gene ID: 147991 | Gene type: protein coding

About DPY19L3

Cytogenetic location: 19q13.11 Genomic coordinates (GRCh38): 19:32,405,770-32,485,890 (from NCBI)

This gene has 12 transcripts (splice variants), 203 orthologues and 3 paralogues. Ubiquitous expression in testis (RPKM 5.7), prostate (RPKM 5.6) and 25 other tissues.

Summary

Predicted to enable mannosyltransferase activity. Predicted to be involved in protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan. Predicted to be integral component of membrane. Predicted to be active in nuclear inner membrane. [provided by Alliance of Genome Resources, Apr 2022]

DPY19L3 Products(2)

mRNA	Protein	Name
NM_001172774.2	NP_001166245.1	probable C-mannosyltransferase DPY19L3
NM_207325.3	NP_997208.2	probable C-mannosyltransferase DPY19L3

DPY19L3 Protein Structure

Dpy19

0
200
400
600
716 a.a.

Protein Preferred Names

Protein Names

probable C-mannosyltransferase DPY19L3

dpy-19 like 3

Related Diseases

Diseases

Alias

Spermatogenic Failure 9

Male Infertility Due To Globozoospermia	SPGF9
Male Infertility Due To Round-Headed Spermatozoa	Globozoospermia, Complete
Globozoospermia, Total	Globozoospermia
Globozoospermia Syndrome	Round-Headed Sperm Syndrome
Globozoospermia Complete	Globozoospermia Total

Podoconiosis

PDCOS	Podoconiosis, Susceptibility To
Nonfilarial Elephantiasis Of Lower Legs	Nonfilarial Elephantiasis Of Lower Legs, Susceptibility To
Endemic Nonfilarial Elephantiasis	Endemic Nonfilarial Elephantiasis, Susceptibility To
Lymphostatic Verrucosis	Lymphostatic Verrucosis, Susceptibility To
Elephantiasis	Endemic Non-Filarial Elephantiasis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03977	DPY19L3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	DPY19L3	MGD	MGI:2443952
Felis catus	DPY19L3	VGNC	VGNC:61612
Rattus norvegicus	DPY19L3	RGD	RGD:1308334
Canis familiaris	DPY19L3	VGNC	VGNC:49600
Macaca mulatta	DPY19L3	VGNC	VGNC:71912
Bos taurus	DPY19L3	VGNC	VGNC:49144

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