Mr1 - major histocompatibility complex, class I-related Gene

Also Known as H2ls

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15064

Summary

Predicted to enable T cell receptor binding activity and beta-2-microglobulin binding activity. Involved in T cell differentiation in thymus and defense response to Gram-negative bacterium. Predicted to be located in endoplasmic reticulum membrane; endosome membrane; and plasma membrane. Predicted to be part of MHC class I protein complex. Predicted to be active in external side of plasma membrane and extracellular space. Orthologous to human MR1 (major histocompatibility complex, class I-related). [provided by Alliance of Genome Resources, Apr 2022]

Mr1 Products (3)

mRNA Protein Name
NM_001355062.1 NP_001341991.1 major histocompatibility complex class I-related gene protein isoform 2
NM_001355063.1 NP_001341992.1 major histocompatibility complex class I-related gene protein isoform 3
NM_008209.5 NP_032235.1 major histocompatibility complex class I-related gene protein isoform 1 precursor
Protein Preferred Names Protein Names

major histocompatibility complex class I-related gene protein

  • MCH class I

  • MHC class I-related gene protein

  • class I histocompatibility antigen-like protein

  • histocompatibility-2 complex class 1-like sequence

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-157282 Photolumazine I / Phase 4

Pre-clinical Phase

Bioactive Molecules (12)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-124004 Acetyl-6-formylpterin 95.0% Unkown
HY-126855 Cholic acid 7-sulfate 99.92% Unkown
HY-32955 2-Chloropyridine-5-boronic acid 99.96% Unkown
HY-W168754 DB28 Inhibitor 99.92% Unkown
HY-157281 Photolumazine III 99.96% Unkown
HY-157194 RL-6-Me-7-OH 96.56% Unkown
HY-182894 MR1-114 Inhibitor / Unkown
HY-P11249 Mr1.1[S4Dap, C16Pen] Inhibitor / Unkown
HY-RS08637 MR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10777 PNKD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-126855S Cholic acid 7-sulfate-d4 / Unkown
HY-163122 5-Formylsalicylic acid 99.54% Unkown
Bioactive MoleculesInhibitory Antibodies (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990134 Anti-Mouse CD40L/CD154 Antibody (MR-1) Inhibitor 99.62% Unkown
HY-P990269 Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1) Inhibitor 95.00% Unkown
HY-P990270 Anti-Mouse CD40L/CD154 (D265A) Antibody (MR-1) / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mr1 NCBI NCBI:3140