Oxr1 - oxidation resistance 1 Gene

Also Known as C7; C7B; 2210416C20Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 170719

Summary

Enables oxidoreductase activity. Acts upstream of or within several processes, including adult walking behavior; negative regulation of neuron death; and negative regulation of peptidyl-cysteine S-nitrosylation. Located in nucleolus. Is expressed in several structures, including central nervous system; genitourinary system; liver; lung; and spleen. Human ortholog(s) of this gene implicated in cerebellar hyplasia/atrophy, epilepsy, and global developmental delay. Orthologous to human OXR1 (oxidation resistance 1). [provided by Alliance of Genome Resources, Apr 2022]

Oxr1 Products (8)

mRNA Protein Name
NM_001130163.1 NP_001123635.1 oxidation resistance protein 1 isoform B
NM_001130164.1 NP_001123636.1 oxidation resistance protein 1 isoform C
NM_001130165.2 NP_001123637.1 oxidation resistance protein 1 isoform D
NM_001130166.1 NP_001123638.1 oxidation resistance protein 1 isoform E
NM_001358976.1 NP_001345905.1 oxidation resistance protein 1 isoform F
NM_001358977.1 NP_001345906.1 oxidation resistance protein 1 isoform E
NM_001358978.1 NP_001345907.1 oxidation resistance protein 1 isoform G
NM_130885.2 NP_570955.1 oxidation resistance protein 1 isoform A

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables oxidoreductase activity IDA
IDA: Inferred from direct assay
22028674 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within adult walking behavior IMP
IMP: Inferred from mutant phenotype
22028674 MGI
acts upstream of or within cellular response to hydroperoxide IMP
IMP: Inferred from mutant phenotype
22028674 MGI
acts upstream of or within negative regulation of cellular response to oxidative stress IDA
IDA: Inferred from direct assay
26668325 MGI
acts upstream of or within negative regulation of cellular response to oxidative stress IMP
IMP: Inferred from mutant phenotype
26668325 MGI
acts upstream of or within negative regulation of neuron apoptotic process IMP
IMP: Inferred from mutant phenotype
22028674 MGI
acts upstream of or within negative regulation of peptidyl-cysteine S-nitrosylation IDA
IDA: Inferred from direct assay
26668325 MGI
acts upstream of neuron apoptotic process IMP
IMP: Inferred from mutant phenotype
22028674 MGI
acts upstream of or within neuron apoptotic process IMP
IMP: Inferred from mutant phenotype
26668325 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleolus IDA
IDA: Inferred from direct assay
11237729 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

oxidation resistance protein 1

  • nucleolar protein C7

  • protein C7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-108683 ACT-335827 Antagonist 98.0% Unkown
HY-RS06051 HCRTR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09890 OXR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20317 Oxr1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26825 Oxr1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Oxr1 NCBI NCBI:55074