Minar2 - membrane integral NOTCH2 associated receptor 2 Gene

Also Known as A730017C20Rik

Species: Mus musculus

Gene Type: protein coding

Gene ID: 225583

Summary

Predicted to be located in membrane. Predicted to be integral component of membrane. Used to study Parkinson's disease. Orthologous to human MINAR2 (membrane integral NOTCH2 associated receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Minar2 Products (2)

mRNA	Protein	Name
NM_001167925.2	NP_001161397.2	major intrinsically disordered NOTCH2-binding receptor 1-like homolog isoform c
NM_173759.5	NP_776120.3	major intrinsically disordered NOTCH2-binding receptor 1-like homolog isoform a

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32954300	MGI

Biological Process GO Annotation	Evidence	References	Source
acts upstream of or within apoptotic process	IMP IMP: Inferred from mutant phenotype	35727972	MGI
acts upstream of or within exploration behavior	IMP IMP: Inferred from mutant phenotype	32954300	MGI
acts upstream of or within gene expression	IMP IMP: Inferred from mutant phenotype	32954300	MGI
acts upstream of or within homeostasis of number of cells within a tissue	IMP IMP: Inferred from mutant phenotype	35727972	MGI
acts upstream of or within inner ear auditory receptor cell differentiation	IMP IMP: Inferred from mutant phenotype	35727972	MGI
acts upstream of or within inner ear receptor cell differentiation	IMP IMP: Inferred from mutant phenotype	35727972	MGI
acts upstream of or within inner ear receptor cell stereocilium organization	IMP IMP: Inferred from mutant phenotype	35727972	MGI
acts upstream of or within locomotory behavior	IMP IMP: Inferred from mutant phenotype	32954300	MGI
acts upstream of or within neuron apoptotic process	IMP IMP: Inferred from mutant phenotype	32954300	MGI
acts upstream of or within sensory perception of sound	IMP IMP: Inferred from mutant phenotype	35727972	MGI
acts upstream of or within walking behavior	IMP IMP: Inferred from mutant phenotype	32954300	MGI

Cellular Component GO Annotation	Evidence	References	Source
is active in endoplasmic reticulum	IDA IDA: Inferred from direct assay	32954300	MGI
located in lysosomal membrane	IDA IDA: Inferred from direct assay	36317962	MGI
is active in stereocilium	IMP IMP: Inferred from mutant phenotype	35727972	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
major intrinsically disordered NOTCH2-binding receptor 1-like homolog	UPF0258 protein KIAA1024-like homolog major intrinsically disordered Notch2-binding receptor 1-like homolog

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08450	MINAR2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Minar2	NCBI	NCBI:100127206