Pik3c2b - phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta Gene

Mus musculus

Also known as Gm199; PI3KC2beta; PI3K-C2beta; C330011J12Rik

Gene ID: 240752 | Gene type: protein coding

About Pik3c2b

Chromosome 1: 132,973,405-133,036,425 forward strand.GRCm39:CM000994.3

This gene has 5 transcripts (splice variants), 207 orthologues and 9 paralogues. Ubiquitous expression in colon adult (RPKM 14.), spleen adult (RPKM 1.9) and 24 other tissues.

Summary

Enables lipid kinase activity. Acts upstream of or within several processes, including autophagosome organization; phosphatidylinositol-3-phosphate biosynthetic process; and protein kinase B signaling. Located in endocytic vesicle. Is expressed in eye; limb; nervous system; and skeleton. Orthologous to human PIK3C2B (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta). [provided by Alliance of Genome Resources, Apr 2022]

Pik3c2b Products(1)

mRNA	Protein	Name
NM_001099276.2	NP_001092746.2	phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta

Pik3c2b Protein Structure

PI3K_rbd

C2A_PI3K_class_II

PI3Ka_II

PI3Kc_C2_beta

PX_PI3K_C2_beta

C2B_PI3K_class_II

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1632 a.a.

Protein Preferred Names

Protein Names

phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta

phosphoinositide-3-kinase, class 2, beta polypeptide

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-112608	CHMFL-PI3KD-317	Inhibitor	98.04%	Unkown
HY-RS10514	PIK3C2B Human Pre-designed siRNA Set A		/	Unkown
HY-RS10515	Pik3c2b Mouse Pre-designed siRNA Set A		/	Unkown
HY-RS10516	Pik3c2b Rat Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pik3c2b	NCBI	NCBI:5287

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