Lrit3 - leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 Gene

Also Known as Gm421

Species: Mus musculus

Gene Type: protein coding
Gene ID: 242235

Summary

Acts upstream of or within visual perception. Predicted to be located in cell projection; endoplasmic reticulum; and membrane. Predicted to be integral component of membrane. Used to study congenital stationary night blindness 1F. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1F. Orthologous to human LRIT3 (leucine rich repeat, Ig-like and transmembrane domains 3). [provided by Alliance of Genome Resources, Apr 2022]

Lrit3 Products (1)

mRNA Protein Name
NM_001287224.2 NP_001274153.1 leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
31959619 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within gene expression IMP
IMP: Inferred from mutant phenotype
31959619 MGI
acts upstream of or within protein localization IMP
IMP: Inferred from mutant phenotype
25997951 MGI
acts upstream of or within response to light stimulus IMP
IMP: Inferred from mutant phenotype
31959619 MGI
acts upstream of or within synapse assembly involved in innervation IMP
IMP: Inferred from mutant phenotype
25997951 MGI
acts upstream of or within synaptic signaling IMP
IMP: Inferred from mutant phenotype
31959619 MGI
acts upstream of or within visual perception IMP
IMP: Inferred from mutant phenotype
24598786 MGI
Cellular Component GO Annotation Evidence References Source
is active in cell tip IDA
IDA: Inferred from direct assay
25997951 MGI
is active in dendrite IDA
IDA: Inferred from direct assay
25997951 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07790 LRIT3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22617 Lrit3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29132 Lrit3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lrit3 NCBI NCBI:345193