HPRT1 - Hprt1 hypoxanthine phosphoribosyltransferase 1 Gene

Also Known as Hprt; Hgprtase

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24465

Summary

Enables hypoxanthine phosphoribosyltransferase activity. Involved in several processes, including cellular response to Insulin stimulus; hypoxanthine metabolic process; and spermatogenesis. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Biomarker of hepatocellular carcinoma. Human ortholog(s) of this gene implicated in HRPT-related hyperuricemia and Lesch-Nyhan syndrome. Orthologous to human HPRT1 (hypoxanthine phosphoribosyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

HPRT1 Products (1)

mRNA Protein Name
NM_012583.2 NP_036715.1 hypoxanthine-guanine phosphoribosyltransferase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables hypoxanthine phosphoribosyltransferase activity IDA
IDA: Inferred from direct assay
6206848 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to insulin stimulus IEP
IEP: Inferred from expression pattern
2185659 RGD
involved in hypoxanthine metabolic process IDA
IDA: Inferred from direct assay
6206848 RGD
involved in spermatogenesis IEP
IEP: Inferred from expression pattern
12193390 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hypoxanthine-guanine phosphoribosyltransferase

  • HGPRT

  • hypoxanthine guanine phosphoribosyl transferase 1

  • hypoxanthine phosphoribosyl transferase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06344 HPRT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W587952 Gibberellin A34 Inhibitor / Unkown
HY-RS18824 Hprt1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25314 Hprt1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens HPRT1 NCBI NCBI:3251