Thrb - thyroid hormone receptor beta Gene
Also Known as ERBA2; Nr1a2; T3rec; TRbeta; RATT3REC; c-erbA-2; C-erba-beta
Species: Rattus norvegicus
Summary
Enables double-stranded DNA binding activity; identical protein binding activity; and nuclear receptor activity. Involved in several processes, including positive regulation of chondrocyte differentiation; positive regulation of ossification; and regulation of lipid metabolic process. Predicted to be located in nuclear body. Used to study breast Cancer. Human ortholog(s) of this gene implicated in several diseases, including cervix uteri carcinoma in situ; prostate cancer; renal cell carcinoma; selective pituitary thyroid hormone resistance; and thyroid hormone resistance syndrome. Orthologous to human THRB (Thyroid Hormone Receptor beta). [provided by Alliance of Genome Resources, Apr 2022]
Thrb Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001270854.1 | NP_001257783.1 | thyroid hormone receptor beta isoform 2 |
| NM_012672.3 | NP_036804.2 | thyroid hormone receptor beta isoform 1 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
thyroid hormone receptor beta |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS14501 | THRB Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS20346 | Thrb Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS26855 | Thrb Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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