IGF2 - insulin like growth factor 2 Gene

Species: Bos taurus

Gene Type: protein coding
Gene ID: 281240

Summary

This gene encodes a member of the Insulin family of protein growth factors, which are involved in fetal development and growth. It is an imprinted gene that is expressed from the paternal allele while the maternal allele is silenced. The encoded protein is proteolytically processed to generate the mature peptide hormone, which binds to receptors of the Insulin Receptor family. This peptide plays a role in oocyte development and folliculogenesis in female cattle. Polymorphisms in this gene may be associated with cattle body mass. [provided by RefSeq, Dec 2018]

IGF2 Products (7)

mRNA Protein Name
NM_001367627.1 NP_001354556.1 insulin-like growth factor II preproprotein
NM_001367628.1 NP_001354557.1 insulin-like growth factor II preproprotein
NM_001367629.1 NP_001354558.1 insulin-like growth factor II preproprotein
NM_001367630.1 NP_001354559.1 insulin-like growth factor II preproprotein
NM_001367631.1 NP_001354560.1 insulin-like growth factor II preproprotein
NM_001367632.1 NP_001354561.1 insulin-like growth factor II preproprotein
NM_174087.4 NP_776512.2 insulin-like growth factor II preproprotein
Protein Preferred Names Protein Names

insulin-like growth factor II

  • IGF-II

  • erythrotropin

  • insulin-like growth factor 2 (somatomedin A)

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive MoleculesInhibitory Antibodies (4)
Cat. No. Product Name Effect
Purity Phase
HY-P99294 Ganitumab Inhibitor 96.00% Phase 3
HY-P99274 Xentuzumab Antagonist 99.71% Phase 2
HY-P99284 Dalotuzumab 97.43% Phase 2
HY-P991253 BIIB022 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (27)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-153274 CWI1-2 Inducer 98.85% Unkown
HY-144873 AVJ16 Inducer 99.60% Unkown
HY-174228 I3IN-002 99.35% Unkown
HY-124447 BTYNB 98.0% Unkown
HY-153274A CWI1-2 hydrochloride Inducer 98.27% Unkown
HY-156110 IGF2BP1-IN-1 Inhibitor 99.94% Unkown
HY-115449 Chromeceptin 99.80% Unkown
HY-176471 IGF2BP3-IN-1 Inhibitor 99.05% Unkown
HY-RS06618 IGF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06619 IGF2BP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06620 IGF2BP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06621 IGF2BP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06622 IGF2R Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17518 Igf2bp3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-181666 Z971169476 / Unkown
HY-E70730 INSR Recombinant Human Active Protein Kinase / Unkown
HY-RS06839 INS-IGF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174653 Human IGF2 mRNA / Unkown
HY-RS16571 Igf2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16822 Igf2bp2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16849 Igf2bp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17981 Igf2r Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23004 Igf2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23262 Igf2bp2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23290 Igf2bp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23975 Igf2bp3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24452 Igf2r Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens IGF2 NCBI NCBI:3481
Mus musculus IGF2 NCBI NCBI:16002
Macaca mulatta IGF2 NCBI NCBI:710802