Ube2k - ubiquitin-conjugating enzyme E2K Gene

Also Known as Lig; Hip2; Hypg; E2-25k

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 289623

Summary

Predicted to enable ubiquitin conjugating enzyme activity; ubiquitin protein Ligase binding activity; and ubiquitin-ubiquitin Ligase activity. Acts upstream of or within intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress. Predicted to be located in cytoplasm and filopodium tip. Predicted to be active in nucleus. Orthologous to human UBE2K (ubiquitin conjugating enzyme E2 K). [provided by Alliance of Genome Resources, Apr 2022]

Ube2k Products (1)

mRNA Protein Name
NM_001106006.1 NP_001099476.1 ubiquitin-conjugating enzyme E2 K

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IMP
IMP: Inferred from mutant phenotype
18710920 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin-conjugating enzyme E2 K

  • huntingtin interacting protein 2

  • ubiquitin-conjugating enzyme E2-25K

  • ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15352 UBE2K Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19042 Ube2k Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25532 Ube2k Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ube2k NCBI NCBI:3093