P2ry2 - purinergic receptor P2Y2 Gene

Rattus norvegicus

Also known as P2Y2

Gene ID: 29597 | Gene type: protein coding

About P2ry2

Primary_assembly 1: 155,351,165-155,367,632 reverse strand.mRatBN7.2:CM026974.1

This gene has 2 transcripts (splice variants), 201 orthologues, 13 paralogues and is associated with 12 phenotypes. Biased expression in Liver (RPKM 266.1), Muscle (RPKM 112.6) and 7 other tissues.

Summary

Enables A1 Adenosine Receptor binding activity; ATP binding activity; and G protein-coupled UTP receptor activity. Involved in several processes, including positive regulation of penile erection; regulation of cytosolic calcium ion concentration; and regulation of secretion by cell. Located in apical plasma membrane and basolateral plasma membrane. Is active in glutamatergic synapse. Is integral component of presynaptic active zone membrane. Colocalizes with early endosome; lysosome; and mitochondrion. Used to study impotence. Orthologous to human P2RY2 (purinergic receptor P2Y2). [provided by Alliance of Genome Resources, Apr 2022]

P2ry2 Products(1)

mRNA	Protein	Name
NM_017255.2	NP_058951.2	P2Y purinoceptor 2

P2ry2 Protein Structure

7tmA_P2Y2

0
100
200
300
374 a.a.

Protein Preferred Names

Protein Names

P2Y purinoceptor 2

ATP receptor	P2U purinoceptor 1
P2U1	P2Y ATP receptor 2
purinergic receptor P2Y, G-protein coupled, 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS09928	P2RY2 Human Pre-designed siRNA Set A	/	Unkown
HY-RS09929	P2ry2 Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS09930	P2ry2 Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	P2ry2	NCBI	NCBI:5029

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