Slc22a5 - solute carrier family 22 member 5 Gene

Also Known as CT1; OCTN2; UST2r

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29726

Summary

Enables (R)-carnitine transmembrane transporter activity. Involved in (R)-carnitine transmembrane transport. Located in basolateral plasma membrane and cytosol. Human ortholog(s) of this gene implicated in Crohn's disease; cardiomyopathy; inherited metabolic disorder; and systemic primary carnitine deficiency disease. Orthologous to human SLC22A5 (solute carrier family 22 member 5). [provided by Alliance of Genome Resources, Apr 2022]

Slc22a5 Products (1)

mRNA Protein Name
NM_019269.1 NP_062142.1 solute carrier family 22 member 5

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables (R)-carnitine transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
28257821 RGD
enables carnitine transmembrane transporter activity IDA
IDA: Inferred from direct assay
9792817 RGD
enables carnitine transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
16322553 RGD
enables quaternary ammonium group transmembrane transporter activity IDA
IDA: Inferred from direct assay
10636865 RGD
enables quaternary ammonium group transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
10454528 RGD
Biological Process GO Annotation Evidence References Source
involved in (R)-carnitine transmembrane transport IDA
IDA: Inferred from direct assay
10454528 RGD
involved in (R)-carnitine transmembrane transport IMP
IMP: Inferred from mutant phenotype
28257821 RGD
involved in carnitine transport IDA
IDA: Inferred from direct assay
9792817 RGD
involved in carnitine transport IMP
IMP: Inferred from mutant phenotype
16322553 RGD
involved in quaternary ammonium group transport IDA
IDA: Inferred from direct assay
10636865 RGD
involved in quaternary ammonium group transport IMP
IMP: Inferred from mutant phenotype
10454528 RGD
Cellular Component GO Annotation Evidence References Source
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
12080034 RGD
located in cytoplasm IDA
IDA: Inferred from direct assay
28257821 RGD
located in cytosol IDA
IDA: Inferred from direct assay
17995936 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
17995936 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

solute carrier family 22 member 5

  • high-affinity carnitine transporter

  • high-affinity sodium-dependent carnitine cotransporter

  • integral membrane transport protein

  • organic cation/carnitine transporter 2

  • solute carrier family 22 (organic cation transporter), member 5

  • solute carrier famil

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13077 SLC22A5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20645 Slc22a5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27155 Slc22a5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc22a5 NCBI NCBI:6584