Alms1 - ALMS1, centrosome and basal body associated protein Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 297408

Summary

Predicted to enable alpha-actinin binding activity and microtubule binding activity. Predicted to be involved in positive regulation of cold-induced thermogenesis and regulation of centriole replication. Predicted to act upstream of or within several processes, including Cholesterol homeostasis; gamete generation; and neuron development. Located in centriole and ciliary basal body. Human ortholog(s) of this gene implicated in Alstrom syndrome. Orthologous to human ALMS1 (ALMS1 centrosome and basal body associated protein). [provided by Alliance of Genome Resources, Apr 2022]

Alms1 Products (1)

mRNA Protein Name
NM_001106604.2 NP_001100074.2 Alstrom syndrome protein 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in positive regulation of endocytosis IMP
IMP: Inferred from mutant phenotype
30385718 RGD
Cellular Component GO Annotation Evidence References Source
located in centriole IDA
IDA: Inferred from direct assay
21071598 RGD
located in ciliary basal body IDA
IDA: Inferred from direct assay
21071598 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

Alstrom syndrome protein 1

  • Alstrom syndrome 1 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00611 ALMS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22387 Alms1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28911 Alms1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Alms1 NCBI NCBI:7840