Ugt1a8 - UDP glucuronosyltransferase family 1 member A8 Gene

Also Known as Ugt1; Ugt1a9; UDPGT 1-8

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 301595

Summary

Enables glucuronosyltransferase activity. Involved in cellular response to organic cyclic compound and coumarin catabolic process. Located in membrane. Human ortholog(s) of this gene implicated in alcoholic pancreatitis and pancreatic Cancer. Orthologous to several human genes including UGT1A8 (UDP glucuronosyltransferase family 1 member A8). [provided by Alliance of Genome Resources, Apr 2022]

Ugt1a8 Products (1)

mRNA Protein Name
NM_175846.2 NP_787040.2 UDP-glucuronosyltransferase 1A8 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables glucuronosyltransferase activity IDA
IDA: Inferred from direct assay
15502008 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to organic cyclic compound IEP
IEP: Inferred from expression pattern
11992647 RGD
involved in coumarin catabolic process IDA
IDA: Inferred from direct assay
15502008 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

UDP-glucuronosyltransferase 1A8

  • A3

  • UDP glycosyltransferase 1 family, polypeptide A8

  • UDP-glucuronosyltransferase 1-8

  • UDPGT

  • UGT1*8

  • UGT1-08

  • UGT1.8

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-130046 16-Epiestriol Inhibitor 99.04% Unkown
HY-135582 Raloxifene 4'-glucuronide Modulator 98.19% Unkown
HY-135581 Raloxifene 6-glucuronide Modulator / Unkown
HY-135581S1 Raloxifene 6-glucuronide-d4 lithium Modulator / Unkown
HY-135582S Raloxifene 4'-glucuronide-d4 Modulator / Unkown
HY-135582S1 Raloxifene 4'-glucuronide-d4 lithium Modulator / Unkown
HY-N19800 Anhydroicaritin-3,7-di-O-glucuronide / Unkown
HY-RS15432 UGT1A8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19083 Ugt1a8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ugt1a8 NCBI NCBI:54576