Sulf2 - sulfatase 2 Gene

Predicted to enable N-acetylglucosamine-6-sulfatase activity; arylsulfatase activity; and glycosaminoglycan binding activity. Predicted to be involved in several processes, including esophagus smooth muscle contraction; regulation of signal transduction; and skeletal system development. Predicted to act upstream of or within several processes, including liver regeneration; positive regulation of canonical Wnt signaling pathway; and regulation of hepatocyte proliferation. Predicted to be located in Golgi stack and extracellular space. Predicted to be active in cell surface; endoplasmic reticulum; and plasma membrane. Orthologous to human SULF2 (sulfatase 2). [provided by Alliance of Genome Resources, Apr 2022]