Lpin1 - lipin 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 313977

Summary

Predicted to enable several functions, including histone deacetylase binding activity; peroxisome proliferator activated receptor binding activity; and phosphatidate Phosphatase activity. Involved in several processes, including negative regulation of myelination; phosphatidic acid biosynthetic process; and regulation of cellular biosynthetic process. Predicted to be located in endoplasmic reticulum and nuclear membrane. Predicted to be part of transcription regulator complex. Predicted to be active in mitochondrial outer membrane and nucleus. Biomarker of end stage renal disease. Orthologous to human LPIN1 (lipin 1). [provided by Alliance of Genome Resources, Apr 2022]

Lpin1 Products (1)

mRNA Protein Name
NM_001012111.1 NP_001012111.1 phosphatidate phosphatase LPIN1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in animal organ regeneration IEP
IEP: Inferred from expression pattern
14718385 RGD
involved in cellular response to insulin stimulus IDA
IDA: Inferred from direct assay
11792863 RGD
involved in negative regulation of myelination IMP
IMP: Inferred from mutant phenotype
21715287 RGD
involved in negative regulation of phosphatidic acid biosynthetic process IMP
IMP: Inferred from mutant phenotype
21715287 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphatidate phosphatase LPIN1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS19455 Lpin1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07769 LPIN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25948 Lpin1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lpin1 NCBI NCBI:23175