Tgif1 - TGFB-induced factor homeobox 1 Gene

Also Known as Tfig; Tgif

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 316742

Summary

Enables co-SMAD binding activity. Involved in cellular response to growth factor stimulus; negative regulation of gene expression; and response to xenobiotic stimulus. Located in nucleus. Biomarker of muscular atrophy. Human ortholog(s) of this gene implicated in holoprosencephaly and holoprosencephaly 4. Orthologous to human TGIF1 (TGFB induced factor homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Tgif1 Products (1)

mRNA Protein Name
NM_001015020.1 NP_001015020.1 homeobox protein TGIF1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables co-SMAD binding IPI
IPI: Inferred from physical interaction
15153551 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to growth factor stimulus IEP
IEP: Inferred from expression pattern
15153551 RGD
involved in negative regulation of gene expression IMP
IMP: Inferred from mutant phenotype
18441095 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
12169274 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein TGIF1

  • TG interacting factor 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14455 TGIF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20113 Tgif1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26617 Tgif1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tgif1 NCBI NCBI:7050