Mdga2 - MAM domain containing glycosylphosphatidylinositol anchor 2 Gene

Also Known as Adp; Mamdc1; 6720489L24Rik; 9330209L04Rik; Tg(Prnp-PFN1*G118V)838Kiaei

Species: Mus musculus

Gene Type: protein coding
Gene ID: 320772

Summary

Involved in regulation of presynapse assembly and regulation of synaptic membrane adhesion. Acts upstream of or within neuron migration and pattern specification process. Located in GABA-ergic synapse. Is active in glutamatergic synapse. Orthologous to human MDGA2 (MAM domain containing glycosylphosphatidylinositol anchor 2). [provided by Alliance of Genome Resources, Apr 2022]

Mdga2 Products (2)

mRNA Protein Name
NM_001193266.1 NP_001180195.2 MAM domain-containing glycosylphosphatidylinositol anchor protein 2 isoform A precursor
NM_207010.2 NP_996893.3 MAM domain-containing glycosylphosphatidylinositol anchor protein 2 isoform B precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23358245 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within gene expression IMP
IMP: Inferred from mutant phenotype
30213953 MGI
acts upstream of or within motor behavior IMP
IMP: Inferred from mutant phenotype
29518482 MGI
acts upstream of or within negative regulation of neuron apoptotic process IMP
IMP: Inferred from mutant phenotype
29518482 MGI
acts upstream of or within neuromuscular process IMP
IMP: Inferred from mutant phenotype
29518482 MGI
acts upstream of or within neuron migration IDA
IDA: Inferred from direct assay
25162227 MGI
acts upstream of or within pattern specification process IMP
IMP: Inferred from mutant phenotype
1633717 MGI
involved in regulation of presynapse assembly IDA
IDA: Inferred from direct assay
27608760 MGI
involved in regulation of presynapse assembly IMP
IMP: Inferred from mutant phenotype
27608760 MGI
involved in regulation of synaptic membrane adhesion IDA
IDA: Inferred from direct assay
27608760 MGI
involved in regulation of synaptic membrane adhesion IMP
IMP: Inferred from mutant phenotype
27608760 MGI
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
27608760 MGI
is active in GABA-ergic synapse IMP
IMP: Inferred from mutant phenotype
27608760 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
27608760 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
27608760 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

MAM domain-containing glycosylphosphatidylinositol anchor protein 2

  • MAM domain containing 1

  • acrodysplasia

Recombinant Mdga2 Proteins

Cat. No. Product Name Accession Purity
HY-P77082 MDGA2 Protein, Mouse (HEK293, His) P60755 (P26-D924) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08259 MDGA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19457 Mdga2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25950 Mdga2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mdga2 NCBI NCBI:161357