CYP27C1 - cytochrome P450 family 27 subfamily C member 1 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 339761

About CYP27C1

This gene has 3 transcripts (splice variants), 171 orthologues and 3 paralogues. Biased expression in skin (RPKM 1.8), urinary bladder (RPKM 0.5) and 11 other tissues.

Summary

This gene encodes a member of the Cytochrome P450 superfamily of Enzymes. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of Cholesterol, Steroids and Other lipids. [provided by RefSeq, Jul 2008]

CYP27C1 Products (3)

mRNA Protein Name
NM_001001665.4 NP_001001665.3 cytochrome P450 27C1 isoform 1
NM_001367501.1 NP_001354430.1 cytochrome P450 27C1 isoform 1
NM_001367502.1 NP_001354431.1 cytochrome P450 27C1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables 11-cis retinal binding IDA
IDA: Inferred from direct assay
27059013 GOA
enables 11-cis-retinal 3,4-desaturase activity IDA
IDA: Inferred from direct assay
27059013 GOA
enables all-trans retinal 3,4-desaturase activity IDA
IDA: Inferred from direct assay
27059013 GOA
enables all-trans retinal binding IDA
IDA: Inferred from direct assay
27059013 GOA
enables all-trans retinoic acid 3,4-desaturase activity IDA
IDA: Inferred from direct assay
27059013 GOA
enables all-trans retinol 3,4-desaturase activity IDA
IDA: Inferred from direct assay
27059013 GOA
enables all-trans-retinol binding IDA
IDA: Inferred from direct assay
27059013 GOA
enables retinoic acid binding IDA
IDA: Inferred from direct assay
27059013 GOA
Biological Process GO Annotation Evidence References Source
involved in retinal metabolic process IDA
IDA: Inferred from direct assay
27059013 GOA
involved in retinoic acid metabolic process IDA
IDA: Inferred from direct assay
27059013 GOA
involved in retinol metabolic process IDA
IDA: Inferred from direct assay
27059013 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CYP27C1 Protein Structure

p450

p450: Cytochrome P450 (2 - 366)

  • 0
  • 100
  • 200
  • 300
  • 372 a.a.
Protein Preferred Names Protein Names

cytochrome P450 27C1

  • all-trans retinol 3,4-desaturase

Related Diseases

Diseases Alias
Keratomalacia

  • Vitamin A Deficiency

  • Night Blindness

  • Retinol Deficiency

  • Xerotic Keratitis

  • VAD

  • Vitamin A

  • Hypovitaminosis A

  • Bitot Spots

  • Bitot Spots In The Young Child

  • Conjunctival Xerosis With Bitot'S Spots

  • Vitamin A Deficiency With Cornea Xerosis

  • Vitamin A Deficiency With Cornea Ulceration Or Xerosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03452 CYP27C1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown