Cadm3 - cell adhesion molecule 3 Gene

Also Known as Igsf4b; Necl-1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 360882

Summary

Predicted to enable protein homodimerization activity. Predicted to be involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to act upstream of or within protein localization. Predicted to be located in cell-cell junction. Predicted to be active in parallel fiber to Purkinje cell synapse. Predicted to be integral component of presynaptic membrane. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease. Orthologous to human CADM3 (cell adhesion molecule 3). [provided by Alliance of Genome Resources, Apr 2022]

Cadm3 Products (2)

mRNA Protein Name
NM_001047103.2 NP_001040568.1 cell adhesion molecule 3 isoform 2 precursor
NM_001412817.1 NP_001399746.1 cell adhesion molecule 3 isoform 1 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in synaptic membrane adhesion IDA
IDA: Inferred from direct assay
18003830 RGD
involved in synaptic membrane adhesion IEP
IEP: Inferred from expression pattern
18003830 RGD
involved in synaptic membrane adhesion IMP
IMP: Inferred from mutant phenotype
18003830 RGD
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
18003830 RGD
is active in GABA-ergic synapse IMP
IMP: Inferred from mutant phenotype
18003830 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
18003830 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
18003830 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cell adhesion molecule 3

  • immunoglobulin superfamily, member 4B

  • nectin-like protein 1

Recombinant Cadm3 Proteins

Cat. No. Product Name Accession Purity
HY-P76757 CADM3 Protein, Rat (HEK293, Fc) Q1WIM3 (N23-H328) ≥ 85%, as determined by reducing SDS-PAGE.
HY-P76758 CADM3 Protein, Rat (HEK293, His) Q1WIM3 (N23-H328) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS18510 Cadm3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01821 CADM3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24992 Cadm3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cadm3 NCBI NCBI:57863