Adprs - ADP-ribosylserine hydrolase Gene

Rattus norvegicus

Also known as Adprhl2

Gene ID: 362600 | Gene type: protein coding

About Adprs

Summary

Predicted to enable O-acetyl-ADP-ribose deacetylase activity; hydrolase activity, acting on glycosyl bonds; and magnesium ion binding activity. Predicted to be involved in DNA repair and peptidyl-serine ADP-deribosylation. Predicted to act upstream of or within cellular response to superoxide. Predicted to be located in cytoplasm; nuclear body; and site of DNA damage. Predicted to be active in mitochondrion and nucleus. Human ortholog(s) of this gene implicated in stress-induced childhood-onset neurodegeneration with variable ataxia and seizures. Orthologous to human ADPRS (ADP-ribosylserine hydrolase). [provided by Alliance of Genome Resources, Apr 2022]

Adprs Products(1)

mRNA	Protein	Name
NM_001108680.1	NP_001102150.1	ADP-ribose glycohydrolase ARH3

Protein Preferred Names

Protein Names

ADP-ribose glycohydrolase ARH3

ADP-ribosylhydrolase like 2

poly(ADP-ribose) glycohydrolase ARH3

Related Agents

Pre-clinical Phase

Bioactive Molecules (17)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-150508	MK-0159	Inhibitor	99.72%	Unkown
HY-146248B	TFMU-ADPr diammonium		98.78%	Unkown
HY-144987	RBN013209	Inhibitor	98.63%	Unkown
HY-171213	NB-3	Inhibitor	99.89%	Unkown
HY-173679	RBN012811		98.79%	Unkown
HY-134354A	pNP-ADPr disodium		98.08%	Unkown
HY-186178	CD38-IN-6	Inhibitor	99.96%	Unkown
HY-146248A	TFMU-ADPr triethylamine		97.26%	Unkown
HY-134261A	8-Br-ADPR disodium	Inhibitor	/	Unkown
HY-134261	8-Br-ADPR	Inhibitor	/	Unkown
HY-134354	pNP-ADPr		/	Unkown
HY-146248	TFMU-ADPr		/	Unkown
HY-181543	CVN14	Inhibitor	/	Unkown
HY-RS00407	ADPRS Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W154247	IP6C	Inhibitor	/	Unkown
HY-134268	8-Br-7-CH-ADPR	Antagonist	/	Unkown
HY-137704	2′-Deoxy-ADPR	Agonist	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Adprs	NCBI	NCBI:54936

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