Adprs - ADP-ribosylserine hydrolase Gene

Predicted to enable O-acetyl-ADP-ribose deacetylase activity; hydrolase activity, acting on glycosyl bonds; and magnesium ion binding activity. Predicted to be involved in DNA repair and peptidyl-serine ADP-deribosylation. Predicted to act upstream of or within cellular response to superoxide. Predicted to be located in cytoplasm; nuclear body; and site of DNA damage. Predicted to be active in mitochondrion and nucleus. Human ortholog(s) of this gene implicated in stress-induced childhood-onset neurodegeneration with variable ataxia and seizures. Orthologous to human ADPRS (ADP-ribosylserine hydrolase). [provided by Alliance of Genome Resources, Apr 2022]