8-Br-7-CH-ADPR

(Synonyms: 8-Bromo-7-deazaadenosine-5'-O-diphosphoribose)

8-Br-7-CH-ADPR (8-Bromo-7-deazaadenosine-5'-O-diphosphoribose) is a specific TRPM2 antagonist that inhibits TRPM2 activation by binding to the NUDT9 homology domain of the TRPM2 channel, thereby controlling the influx of cations through the cell membrane channel. 8-Br-7-CH-ADPR can be used to study the role of TRPM2 in pathological processes such as cell death, neurodegenerative diseases, myocardial infarction, and diabetes.

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  • CAS No.: 1011457-95-6
  • Formule: C16H23BrN4O14P2
  • Masse moléculaire:637.22
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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